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    An in vivo 31P NMR Study of the Accumulation of Phosphoethanolamine by Neuroblastoma Cells as a Function of Their Location in the Tumor in A/J Mice

An in vivo 31P NMR Study of the Accumulation of Phosphoethanolamine by Neuroblastoma Cells as a Function of Their Location in the Tumor in A/J Mice

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We have reported large changes in the concentrations of phosphoethanolamine (PEt) and phosphocholine (PCh) in mouse neuroblastoma cells, the N1E-115 clone of the C1300 tumor, in tissue culture when they were induced to differentiate with DMSO (Glynn, P., et al, Soc, Neurosci. Abstr. , Vol. 12, Part 1, P.320, 1986). In these non-dividing differentiated cells the PEt level exceeded the cytosolic ATP level by more than a factor of 2.