Calcium Regulation of the Neuronal Growth Cone.

The growth cone behaviors that are involved in the generation of neuronal cytoarchitecture are apparently regulated in quite specific ways by calcium. Neurotransmitters and electrical activity, well known for their roles in information coding, have recently been shown to affect growth cone motility by mechanisms linked to calcium. Calcium may therefore act as a common integrator of environmental cues that influence neurite outgrowth and synaptogenesis: in this way calcium may play a key role in the establishment and modulation of brain circuitry.